House of Blues San Diego is located at 1055 5th Avenue, Core-Columbia, Banker’s Hill, San Diego, San Diego County, CAL Fire Southern Region, California, 92101, United States. A beloved venue for locals and tourists alike, House of Blues is renowned for its live music, with talented local and national acts gracing the stage regularly. With a wide variety of musical styles, there is something to please every music fan. In addition to the great music, House of Blues Restaurant & Bar serves up delicious southern inspired cuisine made from scratch. Due to recent circumstances, House of Blues Restaurant & Bar will be temporarily closed until further notice. The safety of our guests, staff, and extended community is always our top priority and we look forward to welcoming you back soon. In the meantime, please stay safe and be sure to check back for updates.