Discover the story of the song > Thorazine Shuffle – Gov’t Mule

The song is talking about how the protagonist can use medication (Thorazine) to make everything seem alright and forget about their pain. They suggest that the person should let go of their pain and let their "monster" side come out and play. In the end, the song says to stay with them until the damage is done, implying that they will continue to use the medication to escape their problems.